The DUTCH test assesses 35 hormones related to sex and adrenal function, including estrogen, progesterone, testosterone, DHEA, and cortisol, along with their metabolites. It also tracks daily free cortisol and cortisone patterns, measures 8-OHdG, melatonin, and nine organic acids, which indicate levels of B12, B6, biotin, glutathione, dopamine, norepinephrine/epinephrine, neuroinflammation, and tryptophan metabolism, providing a comprehensive view of hormonal and metabolic health.
 
The DUTCH test helps pinpoint the underlying causes of sex hormone and adrenal imbalances in men and women. It sheds light on conditions such as PMS, PMDD, PCOS, menopause, infertility, weight gain, fatigue, low libido, sleep problems, and mood disorders in women, as well as infertility, weight gain, fatigue, low libido, sleep issues, mood disorders, and prostate concerns in men. 
 
Tested Biomarkers
2-Methoxy-E1
2-OH-E1
2-OH-E2
4-OH-E1
4-OH-E2
5-Hydroxyindolacetate (5HIAA)
5a-Androstanediol
5a-Dihydrotestosterone (5a-DHT)
5b-Androstanediol
8-hydroxy-2'-deoxyguanosine (8-OHdG)
16-OH-E1
24hr Free Cortisol
24hr Free Cortisone
𝛼-Pregnanediol
𝛼-Tetrahydrocortisol (a-THF)
Androsterone
β-Hydroxyisovalerate
β-Pregnanediol
β-Tetrahydrocortisone (b-THE)
β-Tetrahyrodcortisol (b-THF)
Dehydroepiandrosterone Sulfate (DHEA-S)
Epi-Testosterone
Estradiol (E2)
Estriol (E3)
Estrone (E1)
Etiocholanolone
Homogentisic Homovanillic Acid (HVA)
Indican
Kynurenate
Melatonin
Metabolized cortisol (THF+THE)
Methylation activity (2-Me-E1 / 2-OH-E1)
Methylmalonic Acid (MMA)
Progesterone (Pg) (calculated equivalent)
Pyroglutamate
Quinolinate (Neuroinflammation marker)
Testosterone
Total Dehydroepiandrosterone (DHEA)
Total Oestrogen (Estrogen)
Vanillmandelic Acid (VMA)
Xanthurenate